leprojet | TEXTOS

THE TEXTOS PROJECT

PROJECT OBJECTIVES

The general objective is to develop an innovative 3D matrix for tissue engineering to reconstruct, regenerate or replace the function of deficient tissues or organs. This matrix will constitute a growth support composed of natural polymers. The originality of this project is in the preparation of a two-component, biocompatible and porous sterilized support obtained using a knitting process and ready to use. This material will consist of poly(lactic-co-glycolicacid) (PLGA) as a substrate (providing mechanical function) and chitosan as a surface coating (for biofunctionalization)

The challenges in this project are many. First, a scientific and technical challenge aimed at creating an innovative product at the crossroads of the biotechnology and agri-resources sectors. The second is the maturation of the tissue engineered product, starting from the concept towards the realization of an operational prototype validated in preoperative condition; a key step for the valorization of the product with companies.

All these challenges will be addressed within a consortium bringing together the various complementary areas of expertise belonging to the cross-border area.

the textos approach

The research and development activities that will be undertaken to carry out this project are:

• setting up a new PLGA yarn,
• the coating of these yarns with chitosan and/or the resulting textile structure,
• knitting of a 3D matrix,
• its use in bone reconstruction.

The communication actions, which will be implemented jointly throughout the project, integrate different media for the dissemination of information, event organisation and dissemination to companies.